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Jointly developed by teams from the National Center for Scientific Research (CNRS), the National Institute of Health and Medical Research (INSERM) and the University of Lorraine, and subsequently valued by SATT SAYENS, the technology was acquired by Catsalyze in March 2023.
Catsalyze technology is a revolution. By immobilizing scaffolding proteins such as enzymes or proteins on a protein ring, innovative catalytic objects are created and the benefits are manifold.
This technology is fully in line with green chemistry . By increasing efficiency, increasing production and decreasing costs.
Catsalyze makes the green chemistry economy ever more competitive.
Catsalyze teams have developed a technology that revolutionizes the biologic immobilization of enzymes.
This patented enzymatic scaffolding process is applicable to all proteins and more specifically to enzymes and offers the following possibilities :
Production increase (x5)
By using Catsalyze technology, you will be able to observe an increase in production up to x5 in units of identical production volume.
Our biological scaffolding structures are adapted to harsh conditions such as extreme temperature, salinity, or PH. The scaffolding increases solubility and has a stabilising effect.
Creation of catalytic balls
By covering the C-Ter and N-Ter ends of the ring with enzymes, you can create real catalytic balls.
Increased lifespan and recyclability
More resistance means a longer life. Your enzymes are less fragile. What's more, the scaffolds created are large enough to allow diafiltration processes to be carried out more easily.
Creation of metabolic chains
By grafting two different enzymes onto the ring, you can create a chain reaction system. By stacking rings, we will soon be able to graft many different enzymes and create real catalytic chains.
Improved solubilization and stability
We observed a much better stability and better solubilization of the enzymes when they are produced grafted on the PRX.
By optimizing the structures and optimally exposing the enzymes' active sites, we have observed no loss of activity and even an increase in activity in some enzymes. The structure of the catalytic objects means that many active sites can be grouped around a single structure, creating a synergistic booster effect.
Optimized resin grafting
By immobilizing catalytic balls on resins, we optimize the surface of the resin as much as possible. The resin is better covered, and the active sites are more accessible. The best technology in the world for immobilization on resin.
Research engineer in structural biology - Associate
Engineer in biochemistry - Associate
Research engineer - Associate
Protein biochemistry engineer