One scaffold, twenty display positions, endless possibilities.
Catsalyze designs a decameric protein scaffold capable of displaying enzymes, antigens, nanobodies, peptides or signal molecules with defined copy numbers and orientations. One scaffold, tailored to your target.
Our scaffolding technology
Screening, directed evolution and AI all work on the target protein's sequence and structure. Catsalyze works at a different level: spatial arrangement — how proteins are positioned relative to one another. The scaffold determines distance, orientation, and copy number.
Explore our technologyApplication area
Display multiple copies of enzymes to support catalytic performance and enable easier recovery and reuse.
Biocatalysis in detail →
Display multiple copies of antigens on a single scaffold to create multivalent antigen assemblies.
VLP-like in detail →
Combine binders and reporters on a single scaffold to create sharper diagnostic reagents for target recognition and signal detection.
Diagnostics in detail →
Display 10 to 20 copies of active peptides on a single scaffold to promote avidity and support stability.
Peptides in detail →Natural vanillin via cell-free biocatalysis
From ferulic acid to vanillin, without a living cell: no substrate lost to metabolism, no toxicity, and no cells to keep alive. The scaffold keeps the biocatalyst stable, correctly folded, and easy to reuse under mild aqueous conditions.
Have a scaffolding project in mind?
Propose a project, discuss a licence, or order a ready-to-load, customized scaffold to test on your own target.